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Saturday, September 24, 2011

Risk of diabetes can be reduced by Vitamin D

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Abstract:
According to new meta-analysis increased vitamin D intake that is greater than 500 International Units (IU) per day can reduces the risk of type-2 diabetes by 13%.

Objective:
This study suggest that vitamin D can reduce the risk of diabetes in people with pre-diabetes by improving their beta cell functioning. Vitamin D deficiency is linked to impaired insulin secretion in animal and humans, and also linked to insulin resistance in healthy, glucose-tolerant subjects.

Design:
Researchers from Tuft Medical Centre and Carney Hospital in Massachusetts report that people with the highest blood level of Vitamin D, measured as more than 25 nano-gram per ml, had a 43% lower risk of developing type-2 diabetes than people with the lowest blood levels (less than 14ng/ml).

They divided 92 subjects in 4 groups, with one group receiving the vitamin D, a second group receiving vitamin D and calcium, third group receiving calcium only, and a forth group receiving a placebo. The four-month-study showed that the vitamin D group enjoyed 30% improvement in beta cell function. The other groups showed no similar gain.

Participants:
92 subjects who were considered to have pre-diabetes by virtue of being over weight and having higher than normal blood sugar levels.

Setting or Place:
This research is based on a meta-analysis of 8 observational cohort studies & 11 randomized controlled trials measuring diabetes and vitamin D.

Result:
The result of this study do not show that Vitamin D can prevent the onset of diabetes type-2, only the people with pre-diabetes can take to avoid developing the disease. Maintaining insulin sensitivity and control of blood sugar levels are mainstays in diabetes prevention.

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